The most famous, high quality and effective drug
in preventing breast cancer
More about Nolvadex...
in preventing breast cancer
More about Nolvadex...
Nolvadex 30 pills x 20mg
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Active Ingredient: Tamoxifen
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Nolvadex is an antitumor hormone used to treat breast cancer, breast cancer, kidney cancer, melanoma, and soft tissue sarcoma.
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Nolvadex instructions for use
The active compound in the composition of Nolvadex (Nolvadex) is Tamoxifen (Tamoxifen). This substance belongs to the group of antitumor agents with anti-hormonal activity. Its use is indicated in the treatment of various forms of malignant breast tumors in both men and women, as well as in the treatment of endometrial cancer.
Mechanism of action
Nolvadex (tamoxifen) has the ability to bind to estrogen receptors located on the surface of tumor cells. Thus, it competitively blocks the action of natural estrogen and disrupts one of the important growth mechanisms of estrogen-dependent tumors.
Indications for use
Apply Nolvadex:
- for breast / breast cancer (for adjuvant therapy in women with affected lymph nodes, including metastatic breast cancer in women, breast cancer in men);
- with endometrial cancer,
- with anovulatory infertility.
Contraindications
Not applicable Nolvadex:
- with allergies to the active component;
- with intolerance to auxiliary components;
- with severe thrombocytopenia;
- with leukopenia;
- with hypercalcemia;
- during pregnancy;
- when breastfeeding.
How to take Nolvadex
Nolvadex is administered orally with water.
The standard dose for adults is 20 mg. In the case of a common form of the disease, the dose can be increased to 30-40 mg / day.
The maximum daily dose is 40 mg. An objective response is usually observed after 4-10 weeks of therapy, however, in case of detection of bone metastases, the therapeutic effect can be observed only after several months of taking the drug.
The duration of treatment is determined by the severity, course of the disease. As a rule, treatment is long, lasting until remission is achieved.
There is no need for dose adjustment in elderly patients, patients with impaired renal or hepatic function.
Pregnancy and lactation
The drug should not be used during pregnancy. In pregnant women treated with tamoxifen, there have been isolated cases of spontaneous miscarriage, birth defects, fetal death, but the relationship of these phenomena with tamoxifen has not been established. A study of reproductive toxicity in animals did not reveal teratogenic effects.
A study of intrauterine development in animals showed that drug therapy is associated with changes similar to the effects of estradiol, ethinyl estradiol, clomiphene, diethylstilbestrol.
Before starting therapy, you must make sure that the patient is not pregnant. During the entire period of therapy and at least 3 months after its completion, contraceptive agents must be used.
Do not use oral contraceptives.
It is not known whether the drug is excreted in breast milk, so breast-feeding is stopped during the treatment period.
Side effect
Before you buy Nolvadex, you need to familiarize yourself with the undesirable effects of its use. If such symptoms are found, you should consult a doctor.
- paroxysmal feeling of heat;
- bleeding and vaginal discharge;
- genital itching;
- bone pain
- weight gain with a loss of appetite;
- nausea, sometimes vomiting;
- depressive states;
- constipation
- headaches and dizziness;
- weakness and fatigue;
- increase in body temperature;
- visual impairment;
- skin rash;
- amenorrhea or dysmenorrhea.
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